- Research article
- Open Access
Measuring quality of life of old type 2 diabetic patients in primary care in Portugal: a cross-sectional study
© Prazeres and Figueiredo; licensee BioMed Central Ltd. 2014
Received: 4 January 2014
Accepted: 12 June 2014
Published: 19 June 2014
With the increasing prevalence of diabetes in patients aged over 75, the task of ensuring a good quality of life became even greater. This study aimed to evaluate quality of life of the very elderly (≥75 years) type 2 diabetic primary care patient, in an urban family practice setting.
A cross sectional study was conducted. Quality of life (QoL) was assessed with the Portuguese version of EASY-Care. Descriptive and inferential analyses were performed.
Eighty three elderly type 2 diabetics were included in the study, with a mean age of 80.9 ± 4.3 years old. Most were women, widowed or married, with low educational levels, living with family members in urban areas and presented medium/low incomes. Participants were diagnosed with diabetes for 11.2 ± 10.1 years. Most of them were treated with oral antidiabetic agents, presented complications of diabetes and had good glycemic control. Despite that, excess weight, uncontrolled blood pressure and poor lipid management were noticed.
In general, the participants perceived a positive quality of life. The worst perceived domain was “mental health and well-being”. Within the sociodemographic variables, gender, monthly income, and living arrangements interfered the most with the quality of life domains. Studied clinical variables affected quality of life very modestly.
In an urban primary care setting, when treating very elderly type 2 diabetic patients, and despite good glycemic control, attention should be paid to the QoL of women, the low income diabetics, their living arrangements and thoroughly evaluate the mental health and well-being of these patients.
During the 20th century, and most probably the current one, aging was the most important demographic feature . If in the year 2000 the elderly were represented by 600 million people, it is expected that in 2045 they will surpass the children, in number, worldwide , and 5 years later they will be a growing group of 2 billion .
There is an increased concern about the repercussions of our aging society in the social and health services worldwide but, at the same time, there is also the promotion of the idea that the elderly people need to take an active part in their quality of life through maintenance of mobility and independence .
Since aging has a multitude of patterns there isn’t a consensual definition of quality of life in this age group . “Quality of life” in old age can be characterized as a complex, multidimensional, and holistic concept that includes social, environmental, structural, and health-related aspects .
The impact of aging rises in the old-old (≥75 years) with an increasing likelihood of chronic disease. For the next decade, chronic illnesses have been elected a priority by the WHO , in which Primary Care has an important role, providing comprehensive, person-centred care . One of the biggest challenges of this century is warranting a good quality of life for the elderly, and this task is even greater when we deal with chronic diseases, particularly diabetes. Old age is an important risk factor for diabetes  and diabetes has been accepted as having a negative impact on quality of life . Elderly diabetics show poor physical health and cognitive function in community health settings , particularly when associated with geriatric syndromes, hypoglycemia or diabetes complications , and when living in care homes they have reduced independence QoL scores .
With this study we aimed to examine the perceived quality of life (QoL) of older people with type 2 diabetes aged ≥75 years followed in an urban Family Health Unit and to analyse the associations between sociodemographic and clinical profiles and QoL. For these purposes, we used EASY-Care, which is an assessment instrument recommended by the WHO that establishes a link with quality of life concepts and the measurement of subjective wellbeing, enabling a multidimensional, comprehensive and systematic approach to quality of life in the primary care setting .
Study design and participants
A cross-sectional study was conducted between December 2009 and March 2010, in an urban Family Health Unit in the center region of Portugal. For the purpose of estimating sample size a diabetes prevalence of 26.3%  was used. We determined that a sample of 75 elderly patients (≥75 years old) was the minimum required, with a precision of 10%  and 95% CI, in accordance with 2001 Portuguese population census .
Participants were included if they: were ≥ 75 years old; had previous diagnosis of type 2 diabetes mellitus; had at least 1 appointment in the last 3 months; were able to sign the written informed consent and presented willingness and ability to comply with the study requirements. Participants were excluded if they: presented incapacity and/or inability to attend the interview; were diagnosed with dementia and/or presented inability to understand informed consent; or refused to participate.
The eligible participants were part of a population of 104 individuals aged ≥ 75 years, attending the diabetes clinical care of 6 family physicians. Each person within this population was contacted by telephone or mail address. A total of 83 older persons were included (80% response rate); 7 were excluded due to dementia diagnosis, 5 for being hospitalized, 1 refused to participate and 8 didn’t respond to telephone or letter invitation.
Quality of life related data were collected using the EASY-Care (Elderly Assessment System), adapted to the Portuguese population . This multidimensional instrument, available in 25 European Union countries, evaluates quality of life, well-being, social and health risks of the elderly people aged at least 75 years . Includes the following domains: seeing, hearing and communicating; self-care; mobility; safety; accommodation and finance; staying healthy, mental health and well-being as well as medication administration. The answers to the questions of EASY-Care can be used to calculate three summary scores: i) independence score associated with need for care and support, which can vary between 0 and 100, with higher scores representing greater disability, ii) risk of breakdown in care, predicting the risk of hospital admission and whose score ranges between 0 and 12 points. High scores predict increased risk. iii) risk of falls, whose score ranges from 0 to 8. Three or more positive items indicate a high risk of falls. In addition, a score for each domain can be further calculated. High scores represent a worse perception of quality of life.
EASY-Care is recommended by the WHO to be used in primary and community care settings, to facilitate rapid and multidimensional assessment of older persons and prevent complications and fragilities. The reliability, validity and cost-effectiveness of this instrument have been tested worldwide with promising results [12, 17].
Patient’s sociodemographics were collected by using the personal information section of EASY-Care.
Clinical data were collected from patients’ last appointment by consulting electronic or paper based medical records.
Data were collected in the context of a semi-structured interview. The same person (investigator) conducted all interviews in a private context, a medical office, or at the elderly’s household. The average time of the interview was approximately 1 hour. Data were treated in strict confidentiality to protect the privacy of patients. Each patient was assigned a consecutive number starting at 01.
Data were processed using the statistical program PASW (Predictive Analytics SoftWare) Statistics 18. Descriptive and inferential analyses were performed. Parametric and nonparametric statistical tests were used for dependent (QoL) and independent variables (sociodemographic and clinical profiles). Mann–Whitney U Test was applied to compare the QoL (EASY-Care domains and final scores) between genders (except for the score “risk of breakdown in care” in which we used Independent Samples T-Test, as parametric requirements were fulfilled), living arrangements, duration of diabetes, glycemic control (except for the independence score in which we used Independent Samples T-Test, as parametric requirements were fulfilled). Kruskal-Wallis H Test was applied to compare the QoL (EASY-Care domains and final scores) between age groups (except for the score “risk of breakdown in care” in which we used One-Way ANOVA, as parametric requirements were fulfilled), marital status, scholarity, finances, BMI (except for the score “risk of breakdown in care” in which we used One-Way ANOVA, as parametric requirements were fulfilled), blood pressure, lipid profile, and diabetes-related complications.
A multiple regression was run to predict the summary scores of EASY-Care from the sociodemographic and clinical variables.
We considered statistically significant p values below 0.05.
The study received full approval from the Ethics Committee of the Faculty of Medicine, University of Coimbra and by the Coordinator of the Family Health Unit, where the study took place. The study was conducted in accordance with the principles expressed in the Declaration of Helsinki. Written informed consents were obtained prior to any data collection. Older people who participated in this study were unpaid volunteers.
Study patients’ sociodemographic characteristics
85 and older
With family members
1 to 4 years of education
5 or more years of education
“Not enough to make ends meet”
“Just enough to make ends meet”
“Some money left over”
Study patients’ clinical characteristics
Excellent control (HbA1c < 7,0)
Good control (HbA1c 7,0-8,9)
Marginal control (HbA1c 9,0-9,9)
Bad control (HbA1c ≥ 10,0)
Body Mass Index (kg/m 2 )
Normal (BMI 18,5-24,9)
Overweight (BMI 25–29,9)
Obese (BMI ≥ 30)
Diet and exercise only
Oral therapy only
Insulin only or combined
Only microvascularc complications
Only macrovasculard complications
Microvascular and macrovascular complications
Malignant neoplastic disease
Perceived quality of life
EASY-Care domains (n = 83)
Mean ± SDa
Seeing, hearing and communicating
1.6 ± 1.6
9.8 ± 9.6
3.9 ± 5.1
0.6 ± 0.7
Accommodation and finances
1.0 ± 1.6
1.3 ± 0.7
Mental health and well-being
9.8 ± 3.4
0.5 ± 0.6
Final summary scores of EASY-Care (n = 83)
Mean ± SDa
Risk of falls
1.4 ± 1.2
Risk of breakdown in care or hospital admission
4.2 ± 2.2
14.0 ± 14.9
Analysis between sociodemographics, clinical variables and perceived quality of life
Women reported greater insecurity (p = 0.012) and had a worse perception of their mental health and well-being (p < 0.001) compared to men. Also the risk of breakdown in care or hospital admission was significantly higher in females (p = 0.003).
Participants with a high level of education had an “accommodation and finances” domain score that was significantly different from those that were illiterate (p = 0.036) and from those that had first grade or less (p = 0.044). The first group perceived better accommodation and finances.
Monthly income was significantly associated with five of the eight QoL domains (low-income patients reported worse QoL): (1) seeing, hearing and communicating (p = 0.002); (2) self-care (p = 0.002); (3) mobility (p = 0.048); (4) accommodation and finance (p = 0.010); (5) take medicines (p = 0.005). Low-income patients also presented an increased risk of falling (p = 0.042) and higher need for support (more dependent) (p = 0.001).
Older persons living with family members reported greater difficulty in self-care (p = 0.045) and in taking medicines (p = 0.018). Patients that lived alone manifested greater insecurity (p = 0.043) and worse mental health and well-being (p = 0.021) but greater independence (p = 0.025).
There were no significant differences between age groups and QoL and between marital status and QoL.
Participants with ≤10 years of type 2 diabetes onset reported greater insecurity (p = 0.016) but less difficulty in taking their medicines (p = 0.033).
Interestingly, for those subjects with good glycemic control (HbA1c <7%), greater difficulty in self-care (p = 0.037) was reported.
Well-nourished participants had a significantly higher mobility domain score, compared to those malnourished or at risk of malnutrition (p = 0.041) and to those that were obese (p = 0.013).
There were no significant differences between lipid profiles and QoL and between diabetes complications and QoL.
A multiple regression was run to predict the summary scores of EASY-Care from the sociodemographic and clinical variables. These variables only statistically significantly predicted the Independence Score, F(12, 70) = 3.755, p < 0.0005, adj. R2 = 0.29. Living arrangements, monthly income, and diabetes complications added statistically significantly to the prediction, p < .05.
The analysis of the responses to EASY-Care demonstrates that the majority of the very elderly type 2 diabetic patients had an overall positive quality of life. This finding is consistent with previous literature data, that shows maintenance of independence  and quality of life in older age  even in the context of chronic disease .
The present findings of a worse QoL regarding the domain mental health and well-being might be related to the association of chronic disease with depression  and loneliness  and the link of type 2 diabetes with cognitive decline in old age .
The results of the current study revealed more significant associations between the sociodemographic variables and QoL domains, compared to the clinical variables.
Gender, income and living arrangements interfered with QoL the most. The differences found in gender and income corroborate the results of a previous review, which suggested lower QoL scores for both females and low income diabetics . In line with the previous literature [25, 26] living alone had a negative effect on QoL (domains security and mental health and well-being). Subjects that did not live alone perceived greater difficulty in self-care and with the administration of medication. A possible explanation for this finding may be the fact that old diabetic patients experiment increasing functional impairment, which raises the need for support by a third-person, such as a family member or a caregiver.
In prior studies there is a considerable controversy regarding the relationship between duration of diabetes and quality of life . The present findings demonstrated that there are no statistically significant differences in most domains of the EASY-Care among individuals with longer disease duration (over 10 years), compared to subjects who have diabetes for 10 years or less. These results can be explained by the observation that, in this study, the incidence of complications is independent of the duration of diabetes (chi-square (1) = 0.840, p = 0.359). However, these findings are not supported by the literature  in which patients suffering from chronic complications of diabetes have a longer duration of disease.
The literature is not concordant about the relationship between glycemic control and QoL . The results of this study demonstrate that with exception of self-care, in which participants with good glycemic control reported greater difficulties in this domain, there are no statistically significant differences in other domains of EASY-Care. It seems likely that the deterioration in self-care may be due to the potential adverse effects of hypoglycemia, by maintaining HbA1c levels close to physiological values. Although HbA1c below 7% is recommended for the general diabetic population, this value has been questioned for the elderly diabetics and those with comorbidities [29, 30]. It is advisable, therefore, that an individualized, less rigorous maintenance of low levels of HbA1c should be pursued in these patients [31, 32].
There is a significant impairment of QoL in the obese [33, 34] and also in the malnourished elderly . This study confirms that the well-nourished elderly type 2 diabetic patient has better mobility.
In contrast to earlier findings [25, 36, 37], and except for the Independence Score, no evidence of association of diabetes complications with worse QoL was detected. Given the small sample size and the small number of elderly diabetics with chronic complications, further work is required to establish this with broader samples.
Extrapolation of the study results should be done with caution, regarding bias possibility: unicentral research study, univariate analysis as the main statistical approach, no control group was established, and a diabetes specific QoL questionnaire was not used. Despite these limitations, the use of EASY-Care, a generic instrument aimed to improve the care of the elderly, will allow future comparisons of the results of this study with other groups of elderly people with type 2 diabetes and also with different diseases. Will we find similar results in very elderly patients with other chronic diseases? Upcoming studies will decrease biases by being multicentral, with a defined control group, and by using both generic and specific QoL instruments.
We believe that the findings of this study can make a contribution to daily practice. In an urban primary care setting, when treating very elderly type 2 diabetic patients, and despite good glycemic control, attention should be paid to their QoL, particularly of women and the low income diabetics, their living arrangements and thoroughly evaluate the mental health and well-being of these patients.
- United Nations: World Population Ageing. [http://www.un.org/esa/population/publications/WPA2009/WPA2009_WorkingPaper.pdf]
- CEDRU/BCG: Study to Address the Needs of Senior People. [http://www.akdn.org/publications/2008_portugal_seniors_%20study.pdf]
- Walker A, Mollenkopf H: International and Multi-Disciplinary Perspectives on Quality of Life in Old Age: Conceptual Issues. In Quality of Life in Old Age: International and Multi-Disciplinary Perspectives. Edited by: Mollenkopf H, Walker A. Dordrecht: Springer; 2007:3–13.View ArticleGoogle Scholar
- Trentini CM, Chachamovich E, Fleck MPA: Qualidade de vida em idosos. In A avaliação de qualidade de vida: guia para profissionais de saúde. Edited by: Fleck MPA. Porto Alegre: Artmed S.A; 2008:218–228.Google Scholar
- World Health Organization: Preventing chronic diseases: a vital investment. [http://www.who.int/chp/chronic_disease_report/contents/part1.pdf]
- Rawaf S, De Maeseneer J, Starfield B: From Alma-Ata to Almaty: a new start for primary health care. Lancet 2008, 372(9647):1365–1367. 10.1016/S0140-6736(08)61524-XPubMedView ArticleGoogle Scholar
- Selvin E, Coresh J, Brancati FL: The burden and treatment of diabetes in elderly individuals in the U.S. Diabetes Care 2006, 29(11):2415–2419. 10.2337/dc06-1058PubMedView ArticleGoogle Scholar
- Sikdar KC, Wang PP, MacDonald D, Gadag VG: Diabetes and its impact on health-related quality of life: a life table analysis. Qual life res 2010, 19(6):781–787. 10.1007/s11136-010-9641-5PubMedView ArticleGoogle Scholar
- Wändell PE, Tovi J: The quality of life of elderly diabetic patients. J Diabetes Complications 2000, 14(1):25–30. 10.1016/S1056-8727(99)00066-5PubMedView ArticleGoogle Scholar
- Laiteerapong N, Karter AJ, Liu JY, Moffet HH, Sudore R, Schillinger D, John PM, Huang ES: Correlates of quality of life in older adults with diabetes: the diabetes & aging study. Diabetes Care 2011, 34(8):1749–1753. 10.2337/dc10-2424PubMedPubMed CentralView ArticleGoogle Scholar
- Speight J, Sinclair AJ, Browne JL, Woodcock A, Bradley C: Assessing the impact of diabetes on the quality of life of older adults living in a care home: validation of the ADDQoL Senior. Diabet Med 2013, 30(1):74–80. 10.1111/j.1464-5491.2012.03748.xPubMedView ArticleGoogle Scholar
- Marques A, Martins A, Jácome C, Figueiredo D: Linking the EASY-Care Standard to the International Classification of Functioning. Disability and Health. Disabil Rehabil 2014, 36(7):593–599. 10.3109/09638288.2013.804598PubMedView ArticleGoogle Scholar
- Gardete-Correia L, Boavida JM, Raposo JF, Mesquita AC, Fona C, Carvalho R, Massano-Cardoso S: First diabetes prevalence study in Portugal: PREVADIAB study. Diabet Med 2010, 27(8):879–881. 10.1111/j.1464-5491.2010.03017.xPubMedView ArticleGoogle Scholar
- Suresh K, Chandrashekara S: Sample size estimation and power analysis for clinical research studies. J Hum Reprod Sci 2012, 5(1):7–13. 10.4103/0974-1208.97779PubMedPubMed CentralView ArticleGoogle Scholar
- PORDATA: População por grupo etário. [http://www.pordata.pt/Portugal/Populacao+residente+segundo+os+Censos+total+e+por+grupo+etario-2]
- Sousa L, Figueiredo D: (In)dependência na população idosa: um estudo exploratório na população portuguesa. Psychol 2003, 33: 109–122.Google Scholar
- Olde-Rikkert MG, Long JF, Philp I: Development and evidence base of a new efficient assessment instrument for international use by nurses in community settings with older people. Int J Nurs Stud 2013, 50(9):1180–1183. 10.1016/j.ijnurstu.2012.08.007PubMedView ArticleGoogle Scholar
- World Health Organization: Obesity: preventing and managing the global epidemic. [http://whqlibdoc.who.int/trs/WHO_TRS_894.pdf]
- Ferry M, Alix E: A nutrição da pessoa idosa: aspectos fundamentais, clínicos e psicossociais. Lusociência: Loures; 2004.Google Scholar
- World Health Organization: A life course perspective of maintaining independence in older age. [http://whqlibdoc.who.int/hq/1999/WHO_HSC_AHE_99.2_life.pdf]
- Young Y, Frick KD, Phelan EA: Can successful aging and chronic illness coexist in the same individual? A multidimensional concept of successful aging. J Am Med Dir Assoc 2009, 10(2):87–92. 10.1016/j.jamda.2008.11.003PubMedView ArticleGoogle Scholar
- Chapman DP, Perry GS, Strine TW: The vital link between chronic disease and depressive disorders. Prev Chronic Dis 2005, 2(1):A14.PubMedPubMed CentralGoogle Scholar
- Pinquart M, Sörensen S: Risk factors for loneliness in adulthood and old age--a meta-analysis. In Advances in psychology research. Edited by: Shohov SP. Hauppauge: Nova Science Publishers; 2003:111–143.Google Scholar
- Hassing LB, Grant MD, Hofer SM, Pedersen NL, Nilsson SE, Berg S, McClearn G, Johansson B: Type 2 diabetes mellitus contributes to cognitive decline in old age: a longitudinal-based study. J Int Neuropsychol Soc 2004, 10(4):599–607. 10.1017/S1355617704104165PubMedView ArticleGoogle Scholar
- Rubin RR, Peyrot M: Quality of life and diabetes. Diabetes Metab Res Rev 1999, 15(3):205–218. 10.1002/(SICI)1520-7560(199905/06)15:3<205::AID-DMRR29>3.0.CO;2-OPubMedView ArticleGoogle Scholar
- Hanestad BR: Self-reported quality of life and the effect of different clinical and demographic characteristics in people with type 1 diabetes. Diabetes Res Clin Pract 1993, 19(2):139–149. 10.1016/0168-8227(93)90107-GPubMedView ArticleGoogle Scholar
- Fowler MJ: Microvascular and macrovascular complications of diabetes. Clin Diabetes 2008, 26(2):77–82. 10.2337/diaclin.26.2.77View ArticleGoogle Scholar
- Snoek FJ: Quality of life: a closer look at measuring patients' well-being. Diabetes Spectr 2000, 13: 24–28.Google Scholar
- Currie CJ, Peters JR, Tynan A, Evans M, Heine RJ, Bracco OL, Zagar T, Poole CD: Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study. Lancet 2010, 375(9713):481–489. 10.1016/S0140-6736(09)61969-3PubMedView ArticleGoogle Scholar
- Calles-Escandón J, Lovato LC, Simons-Morton DG, Kendall DM, Pop-Busui R, Cohen RM, Bonds DE, Fonseca VA, Ismail-Beigi F, Banerji MA, Failor A, Hamilton B: Effect of intensive compared with standard glycemia treatment strategies on mortality by baseline subgroup characteristics: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Diabetes Care 2010, 33(4):721–727. 10.2337/dc09-1471PubMedPubMed CentralView ArticleGoogle Scholar
- Kirsh SR, Aron DC: Choosing targets for glycaemia, blood pressure and low-density lipoprotein cholesterol in elderly individuals with diabetes mellitus. Drugs Aging 2011, 28(12):945–960. 10.2165/11594750-000000000-00000PubMedView ArticleGoogle Scholar
- American Diabetes Association: Executive summary: standards of medical care in diabetes–2013. Diabetes Care 2013, 36(Suppl 1):S4-S10.Google Scholar
- Banegas JR, López-García E, Graciani A, Guallar-Castillón P, Gutierrez-Fisac JL, Alonso J, Rodríguez-Artalejo F: Relationship between obesity, hypertension and diabetes, and health-related quality of life among the elderly. Eur J Cardiovasc Prev Rehabil 2007, 14(3):456–462. 10.1097/HJR.0b013e3280803f29PubMedView ArticleGoogle Scholar
- Kolotkin RL, Meter K, Williams GR: Quality of life and obesity. Obes Rev 2001, 2(4):219–229. 10.1046/j.1467-789X.2001.00040.xPubMedView ArticleGoogle Scholar
- Vetta F, Ronzoni S, Taglieri G, Bollea MR: The impact of malnutrition on the quality of life in the elderly. Clin Nutr 1999, 18(5):259–267. 10.1016/S0261-5614(98)80022-8PubMedView ArticleGoogle Scholar
- Coffey JT, Brandle M, Zhou H, Marriott D, Burke R, Tabaei BP, Engelgau MM, Kaplan RM, Herman WH: Valuing health-related quality of life in diabetes. Diabetes Care 2002, 25(12):2238–2243. 10.2337/diacare.25.12.2238PubMedView ArticleGoogle Scholar
- Anderson RM, Fitzgerald JT, Wisdom K, Davis WK, Hiss RG: A comparison of global versus disease-specific quality-of-life measures in patients with NIDDM. Diabetes Care 1997, 20(3):299–305. 10.2337/diacare.20.3.299PubMedView ArticleGoogle Scholar
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