Predictors of dietary supplement use among female health workers in Tehran
© Baygi et al.; licensee BioMed Central Ltd. 2013
Received: 2 December 2012
Accepted: 1 June 2013
Published: 8 June 2013
Despite the lack of evidence on the necessity of dietary supplements to meet nutrients requirements, the majority of people use them all over the world. This study aimed to investigate factors associated with supplement use in women who work in health centers in the city of Tehran.
Five hundred sixty three female health workers participated in a cross-sectional study carried out in 2010 in health centers of Tehran. Weight, height, and waist circumference were measured and body mass index was calculated. Data on demographic characteristics, lifestyle, and dietary supplement use were collected by interviewing. The analysis was conducted using univariate and multivariate logistic regression (MLR) in SPSS version 16.
The prevalence of dietary supplement use was 53.8%. In univariate logistic regression model, age, education, husband’s education, duration of employment, and tendency for changing weight at the time of the study were statistically significant predictors (P < 0.05). After MLR analysis, education (OR: 1.11, 95% CI: 1.05-1.17) and duration of employment (OR: 1.04, 95% CI: 1.02-1.06) remained significant in the model. Women with higher education and longer duration of employment had more tendency to use nutrient supplements.
Our findings showed that education and duration of employment were the most important predictors for taking dietary supplements in this population.
KeywordsDietary supplement Lifestyle Health worker Women Body mass index
Despite the lack of evidence on the necessity of dietary supplements to meet nutrient requirements, the majority of people use them all over the world [1, 2]. Recent studies showed that estimated prevalence of dietary supplement use is higher than those derived from previous surveys [1–3]. While many dietary supplements are safe at certain periods for most people to use , there is growing evidence that some type of supplements can cause serious adverse effects or have no beneficial effects [5–7]. Nowadays, numerous types of supplements have been available in Iran and it seems that their usage is more popular than previous years. Health workers have an important role in educating people who attend the health centers and their nutritional and health behaviors may influence the attendants. Since there is no documentary on the frequency of use and the predictors of supplement intake among health workers, this study was performed to assess some demographic characteristics and life style factors associated with dietary supplement use in women who work in health centers of Tehran.
Material and methods
This study was approved by the ethics committee of Tehran University of Medical Sciences (TUMS). Five hundred sixty three volunteered female health workers participated in this cross-sectional study conducted in 2010 in Tehran. All health centers in Tehran are affiliated to two main medical universities (Tehran and Shahid Beheshti). A single stage stratified cluster sampling method was used to select participants. For sampling, the list of all health centers (n=325) and the frequency of their employees were prepared, as the sampling frame. These centers were stratified by the two universities. Simple random sampling was employed with probability proportional to the size of each stratum. Forty three centers affiliated to Tehran University and 73 centers affiliated to Shahid Beheshti University were selected. Each center was considered as a cluster and all women who were working at each selected center were invited to participate in the study. Subjects reported information about demographic data and lifestyle. In addition, they were asked about their use of dietary supplement in the preceding month of the study and the reasons for taking the supplements. The individual’s perception of health status was determined by self-rated health status questionnaire asking this question “ how would you rate your overall health status: excellent, good, average, poor, or very poor?” The participants’ responses were then categorized in three levels of excellent / good, average, poor / very poor . Physical activity was measured very briefly by asking a question about the level of physical activity of subjects in their own view.
Height was measured by a stadiometer (Seca, Germany) in a standing position with bare feet (precision 0.5 cm), and body weight was determined with subjects wearing light clothes and no shoes or socks, using an electronic balance. Body mass index was calculated as weight (kg)/ squared height (m2). Waist circumference was measured at the level of the midway between the lowest rib and the iliac crest.
Data were analyzed using the SPSS 16 for Windows (SPSS Chicago, IL). The crude odds ratio (OR) were computed by using logistic regression test to establish the degree of association between examined factors and dietary supplement use. Multiple logistic regression (MLR) model was fitted to data to adjust for confounders. All variables that had P < 0.05 in the univariate analysis were fitted into the stepwise multivariate model. Results of the MLR are presented by OR and 95% confidence interval. P-values less than 0.05 were considered as statistically significant.
Frequency of supplement usage and prescription by physician in studied subjects
Frequency of usage N (%)
Prescribed by physician N (%)
Association between quantitative variables and dietary supplement use in univariate logistic regression model
37.8 ± 8.8
35.8 ± 9.1
15.37 ± 3.03
14.52 ± 3.4
Husband’s education (year)
15.74 ± 3.28
14.4 ± 4.002
Duration of employment (year)
12.6 ± 8.4
10.3 ± 8.5
2.8 ± 0.47
2.7 ± 0.49
2.12 ± 1.066
1.95 ± 1.068
BMI (kg/m 2 )
25.71 ± 4.43
25.53 ± 4.46
83.96 ± 10.37
82.97 ± 10.2
1.84 ± 0.91
1.89 ± 0.854
2.29 ± 1.22
2.32 ± 1.17
Association between qualitative variables and dietary supplement use in univariate logistic regression model
1-2 times per week
≥3 times per week
Tendency for weight change at the study time
Try for weight change in last year
Health status now
Health status in past
In the current study 53.8% of participants used dietary supplements. This rate is lower than the rate among women in California-USA  and much more than the rate among adults in Alberta , Korea  and Jordan . In Norway 58% of adult women used dietary supplements whereas in Sweden 43% of women reported taking all kinds of supplements .
In older subjects who were employed for longer times, the prevalence of supplement use was higher. In MLR, both age and duration of employment were fitted into the model, and because of the co-linearity between these two variables, only employment duration, which was associated with age, remained significant. In Norway, Sweden and Denmark, similar to our study, the supplement use increased with age . In a survey of British women in 33–72 years old age group, 61% of the participants took dietary supplements . Foote and her colleague  showed that older individuals were more likely to use supplements. The findings of Frank et al.  are also similar to the results found in the present survey. It seems that supplement use may have already been an established behavior associated with increasing age. Iron and folate intake is more common among middle aged women susceptible to anemia while Calcium/vitamin D is taken more by older adults which are at higher risk for osteoporosis. This relationship was not assessed in present study.
In the present study, subjects with higher education were more likely to use dietary supplements; however, there was no relationship between husband’s education and subjects’ supplement use in multiple logistic regression. Gordon and her colleagues found that supplement use was significantly higher among women who had higher levels of education so that education beyond high school was the strongest predictor of using supplements . Educational status and supplement use were assessed in a survey carried out in Denmark in 2001. The use of supplements increased with increasing length of education in similarity with Sweden and Norway . This relationship might be explained by the increased concern and awareness of a healthy lifestyle among the classes with higher education, which is shown by choosing to take dietary supplements.
There is no relationship between physical activity and dietary supplement use. Our finding is in contrast with other studies that found higher use of dietary supplement among individuals who were more physically active [11, 16, 17]. In this study, physical activity was measured very briefly, which may not reflect actual physical activity level of the subjects. Based on our finding more investigation on physical activity and supplement usage is needed.
No association was observed between health status and supplement use; however, in other studies, subjects with good health status use more supplements [18, 19]. Gordon and her colleagues showed that some health conditions (arthritis, depression) were significantly associated with higher likelihood of using some kinds of supplements, while another (diabetes) was associated with lower likelihood of use . We think the controversy between our results may be related to this concept that we did not ask the presence of any chronic health problem among subjects in detail and we know it may have affected the results.
We did not find any association between BMI and supplement use. But in some studies obesity was inversely associated with supplement use [14, 20, 21]. Investigators think this result might indicate a greater awareness of health and healthy lifestyle among normal weight and lean subjects than obese ones .
There was no association between marital status and supplement use but in a study of elderly Japanese men the results showed that married men were more likely to take vitamins than singles. The investigators of this study believed that family and friends can influence taking dietary supplements . In a study performed by the University of Florida the results showed that those who are unmarried are more likely to use herbs than those who are married, but this difference is not seen in vitamin or mineral supplement use .
This study had some limitations which may have influenced the findings. First, Physical activity was measured very briefly and we think it may not reflect actual physical activity level of the subjects. Based on our findings more investigation on physical activity and supplement usage is needed. Second, we did not ask the presence of any chronic health problem from subjects in detail and it may have confounded our results. Despite this limitation, the current study provides some data on supplement use in a major group of women.
Our findings revealed that women with higher education and employment duration were more likely to use dietary supplements. We suggest that priority be given to promote research on the safety and effectiveness of commonly used dietary supplements. Educational strategies to prevent the dietary supplement use without prescription by nutritionist or physicians are necessary. Public education for unsustainable use of dietary supplement should be targeted. Also development of guidelines for recommending dosages based on age, weight, and health history are strongly recommended.
We thank all the women who participated in this study. Valuable comments by Dr. Fatemeh Mohammadi are hereby acknowledged.
- Gahche J, Bailey R, Burt V, et al. NCHS data brief. In Dietary Supplement Use Among U.S. Adults Has Increased Since NHANES III (1988–1994). Volume 61. Hyattsville, MD: National Center for Health Statistics; 2011.Google Scholar
- Connera M, Kirkb S, Cadeb J, Barrett J: Why do women use dietary supplements? The use of the theory of planned behaviour to explore beliefs about their use. Soc Sci Med 2001, 52: 621–633. 10.1016/S0277-9536(00)00165-9View ArticleGoogle Scholar
- Gordon NP, Schaffer DM: Use of dietary supplements by female seniors in a large Northern California health plan. BMC Geriatr 2005, 5: 4. 10.1186/1471-2318-5-4PubMed CentralView ArticlePubMedGoogle Scholar
- Prentice RL: Clinical trials and observational studies to assess the chronic disease benefits and risks of multivitamin-multimineral supplements. Am J Clin Nutr 2007,85(1):308S-313S.PubMedGoogle Scholar
- Kirk S, Cade JE, Barrett J, Conner M: Diet and lifestyle characteristics associated with dietary supplement use in women. Public Health Nutr 1999,2(1):69–73.View ArticlePubMedGoogle Scholar
- Morris MS, Sakakeeny L, Jacques PL, Picciano MF, Selhub J: Vitamin B-6 intake is inversely related to, and the requirement is affected by. Inflammation Status J Nutr 2010, 140: 103–110.PubMedGoogle Scholar
- Bailey RL, Dodd KW, Gahche JJ, et al.: Total folate and folic acid intake from foods and dietary supplements in the United States: 2003–2006. Am J Clin Nutr 2010, 91: 231–237. 10.3945/ajcn.2009.28427PubMed CentralView ArticlePubMedGoogle Scholar
- Wang JJ, Smith W, Cumming RG, Mitchell P: Variables determining perceived global health ranks: findings from a population-based study. Ann Acad Med Singapore 2006, 35: 190–197.PubMedGoogle Scholar
- Robson PJ, Siou GL, Ullman R, Bryant HE: Sociodemographic, health and lifestyle characteristics reported by discrete groups of adult dietary supplement users in Alberta, Canada: findings from the tomorrow project. Public Health Nutr 2008,11(12):1238–1247. 10.1017/S136898000800219XView ArticlePubMedGoogle Scholar
- Ock SM, Hwang SS, Lee JS, Song CH, Ock CM: Dietary supplement use by South Korean adults: Data from the national complementary and alternative medicine use survey (NCAMUS) in 2006. Nutr Res Pract 2010,4(1):69–74. 10.4162/nrp.2010.4.1.69PubMed CentralView ArticlePubMedGoogle Scholar
- Suleiman AA, Alboqai OK, Yasein N, Al-Essa MK, El Masri K: Prevalence of vitamin-mineral supplement use among Jordan University students. Saudi Med J 2008,29(9):1326–1331.PubMedGoogle Scholar
- Knudsen VK, Rasmussen LB, Haraldsdottir J: Use of dietary supplements in Denmark is associated with health and former smoking. Public Health Nutr 2001,5(3):463–468.Google Scholar
- Kirk SFL, Cade JE, Barrett JH, Conner M: Diet and lifestyle characteristics associated with dietary supplement use in women. Public Health Nutr 1999, 2: 69–73.View ArticlePubMedGoogle Scholar
- Foote JA, Murphy SP, Wilkens LR, et al.: Factors associated with dietary supplement use among healthy adults of five ethnicities. Am J Epidemiol 2003, 157: 888–897. 10.1093/aje/kwg072PubMed CentralView ArticlePubMedGoogle Scholar
- Frank E, Bendich A, Denniston M: Use of vitamin-mineral supplements by female physicians in the United States. Am J Clin Nutr 2000, 72: 969–975.PubMedGoogle Scholar
- Spencer EH, Bendich A, Frank E: Vitamin and mineral supplement use among US medical students: A longitudinal study. J Am Diet Assoc 2006,106(12):1975–1983. 10.1016/j.jada.2006.09.003View ArticlePubMedGoogle Scholar
- Radimer K, Bindewald B, Hughes J, Ervin B, Swanson C, Picciano MF: Dietary supplement use by US adults: data from the National Health and Nutrition Examination Survey, 1999–2000. Am J Epidemiol 2004,160(4):339–349. 10.1093/aje/kwh207View ArticlePubMedGoogle Scholar
- Ervin RB, Wright JD, Kennedy-Stephenson J: Use of dietary supplements in the United States, 1988–1994. Vital Health Stat. 1999, 244: 1–14.Google Scholar
- Lyle BJ, Mares-Perlman JA, Klein BEK, Klein R, Greger JL: Supplement users differ from nonusers in demographic, lifestyle, and dietary and health characteristics. J Nutr 1998, 128: 2355–2362.PubMedGoogle Scholar
- Houston DK, Johnson MA, Daniel TD, et al.: Health and dietary characteristics of supplement users in an elderly population. Int J Vitam Nutr Res 1997, 67: 183–191.PubMedGoogle Scholar
- Nayge RM, Reed DB: Factors associated with the intake of dietary supplements. Fam Econ Nutr Rev 1999, 12: 43–48.Google Scholar
- Kato K, Nomura A, Stemmermann G, Chyou P: Vitamin supplement use and its correlates among elderly Japanese men residing on Oahu. Hi. Public Health Report 1992,106(7):712–717.Google Scholar
- Dana Fennell MA: Determinants of supplement usage. Prev Med 2004, 39: 932–939. 10.1016/j.ypmed.2004.03.031View ArticlePubMedGoogle Scholar
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